Jirocho and Gin battle Kada's elite Harusame forces while the rest of the denizens of Kabuki-cho take on her main forces in the streets. Kada is utterly stunned when her elite forces are beat by just these two humans, and flees the scene. Gin then helps Jirocho resolve his issues regarding Tatsugoro; Otose and Jirocho reconcile at the hospital. Outside the hospital, Kada desperately launches one last feeble attempt at conquering Kabuki-cho, but is stopped in her tracks by Pirako and the Yorozuya - Kada settles for swearing that the Harusame will be back, and flees yet again. At the very end, Jirocho denounces all other names he has ever been called except for Father of Pirako, and goes with his daughter back to the country.

Gintama meets Sket Dance! But not without trouble...

The Renho join forces with Sakamoto and the Yorozuya against Dark Vader and their home planet in order to bring peace to the universe.

Tetsunosuke has been ordered to deliver a letter for Hijikata. However, he's captured by the radical Joi Check It Out gang in the process. Tetsunosuke had concealed his identity to join the gang, but now they know that he has connections to the police. He's taken hostage as leverage over the Shinsengumi and Mimawarigumi. However, the Mimawarigumi shows no concern for the hostage and plots to place the blame squarely on the Shinsengumi. Hijikata and the other members are enraged after learning Isaburo's plans. The Shinsengumi and Mimawarigumi are now in an all-out fight.

After Gintoki saves Tama from Kintoki, he finds the whole town turned against him after Kintoki frames him for the attack! Now Gintoki must face not only Kintoki, but all his former friends too! However, some of them are beginning to have doubts.

Gintoki and the gang storm the palace looking for Maizo and Sadasada, the former Shogun. They find and confront Sadasada, but he still has a few tricks up his sleeve...

Gin finds a strange clock and accidentally breaks it, causing all time in the universe to come to a stop.

Asaemon confronts Yaemon, but after he reveals that it was Gintoki who was the reason for her father's death, her resolve waivers. Will her blade strike Yaemon or Gintoki?

Gin and Hijikata find Gengai, who's newest invention is responsible for their body swapping. He tries to reverse the process but it doesn't work as something is missing. Gin remembers that part of his soul ended up in a dead cat which they must now find. Unfortunately, the Shinsengumi, with their new found freedom, and Odd Jobs, with their new strict codes, seem intent on getting in their way.

Zura, having successfully infiltrated the Shinsengumi, now attempts to get rid of Wolfro, deeming him a threat.

As Gintoki and Takasugi continue their frenzied fight, the past they shared together with Katsura is revealed, as well as the fate of their teacher, Shouyou.