Party Zone was MTV Europe's longest-running show, born not only when MTV Europe started but also when club culture was at its embryonic stage. Partyzone played a mix of new and old tracks from many different genres of dance music, including garage, house, techno, electronic, trance and drum and bass. It can be seen every Friday and Saturday night on the various European local MTV versions, alongside the original MTV European, which still goes out to European countries that don't have a local MTV.

From 1987 - 2000, Party Zone was produced and programmed by James Hyman.

Between 1987 and 1990, Party Zone was hosted by some of MTV Europe's original VJs including Kristiane Backer. From 1991 to late 1998, it was hosted by Simone Angel, who quickly became the "face" of dance music on the channel, interviewing the most groundbreaking electronic acts and promoting videos by then still relatively unknown acts, such as The Prodigy in the early '90s. Party Zone featured many rare interviews over the years, including one with Aphex Twin, The Future Sound of London, Ken Ishii.

Even after Simone Angel left MTV Europe in December 1998, the Party Zone continued to air as a weekly non-stop dance music mix on MTV Europe and on the then newly created local versions.