Season 1 of Oh My Venus premiered on November 16, 2015.

Kim Youngho is a personal trainer for Hollywood stars. He reluctantly comes back to Korea to face his family after a scandal with an actress. Even though he comes from a wealthy family background, he suffered a devastating injury during his childhood days. Now, he overcomes his problems with living a healthy lifestyle. Kang Jooeun is a 33-year-old lawyer who was once the beauty of her school, nicknamed "Daegu's Venus". Over the years she has become overweight and unhealthy. She gets dumped by her boyfriend of 15 years. Jooeun meets Youngho, who agrees to be her personal trainer to help her get healthier. As they work on her physical transformation, they both discover they have feelings for each other. As they grow closer, they heal each other's emotional wounds and fall in love.