通過霍克斯的內部偵查，得到了死柄木率領的敵人聯盟“超常解放戰線”崛起情報的職業英雄和警察們，為了消滅敵人而集結，進行最大規模的作戰。在那裡，也有雄英高中英雄科的學生們的身影。然後英雄們終於進入了“超常解放戰線”的基地群訝山莊和有醫生在的蛇腔醫院！英雄們馬上抓獲醫生，不過，在那裡大量的腦無出現！一下子湧近戰鬥。終於，英雄和敵人的全面戰爭——！

為了抓獲醫生而衝進蛇腔醫院的恩德瓦等人與大量的腦無交戰。No.5英雄米爾科先行追趕醫生，醫生喚醒最強的腦無“高端”。擁有壓倒性力量的高端，米爾科獨自前往…！？另一方面，以群詫山莊為目標的英雄們中，也有可以遠距離、廣域攻擊的常暗和上鳴的身影。同班同學們儘管是支援角色的後衛，但被任命為前衛的上鳴感到不安。那個時候午夜的聲音…。於是，擁有超常解放戰線的強有力的“個性”的敵人出現！

Inside Gunga Villa, the Paranormal Liberation Front realizes that they are under attack, and Twice confronts Hawks about his betrayal.

An enraged Dabi confronts Hawks after Twice's death, meanwhile at the Hospital Endeavor, Eraser head, Crust, Present Mic and X-less finally arrive to help Mirko, who's risking her life to stop Shigaraki's awakening.

The fight against the High-End Nomus in Jaku Hospital continues however they are unaware that Tomura Shigaraki has awakened. Whilst this is happening, Tokoyami flies in to try and save Hawks from Dabi.

Gigantomachia and the rest of the Paranormal Liberation Front gain the upper hand at the Gunga Mountain Villa as the newly awakened Tomura Shigaraki finds a new objective; steal One for All from Izuku Midoriya.

The fight against Shigaraki continues while other heroes fight the new Nomus that Shigaraki summoned. While this is happening Team Edgeshot tries to stop Gigantomachia from making it to Jaku City.

The pro heroes' defensive net was broken through. Facing the monstrous giant are the U.A. hero course students. Class A and Class B work together to start a big operation to block Gigantomachia.

As Aizawa seems to be out of the battle, Midoriya tries to keep Shigaraki in the air utilizing all of his quirks. Knowing his limit is near, Bakugo comes up with a plan to help him.

Shigaraki's attack pierced right through Kacchan. Deku loses himself to his rage and thrust himself to Shigaraki. However, things change suddenly. In the world of One For All, Deku stand against Shigaraki and All For One.

As Ochaco and Toga exchange words and blows, Gigantomachia reaches Shigaraki and the heroes, and Dabi reveals the secret of his past.

Best Jeanist appears and spins together the hopes of all the heroes in this fight as the climax of the all-out war draws near.

Thinking of his great-great-grandfather, Mr. Compress performs his greatest trick in order to save the League of Villains.

Under All For One's control, Shigaraki attacks Tartarus with the Nomus to free All For One's body, freeing many other prisoners in the process.

As heroes deal with criticism from the public, Hawks thinks back on his past with his family, and Endeavor's family visits him in the hospital.

Endeavor and his family reflect on Toya's past and the events that led to his death, and Hawks and Best Jeanist bring them a proposition.

Inside One For All, Izuku talks with the past wielders as the top three heroes deal with public sentiment after Dabi's revelation.

After Izuku decides not to go back to U.A., he finds himself facing Muscular, who was broken out of jail, again and uses the Quirks of the past wielders against him.

The top three heroes continue to face criticism as they deal with jailbreakers and look for hints about All For One and Shigaraki's whereabouts, and Izuku comes across a villain from Tartarus.

During Izuku's fight with Lady Nagant, she tells him secrets about hero society that further solidify his resolve to help those who need his help.

As Izuku goes off alone in his quest for justice, his classmates realize something is wrong and try to find a way to help him.

As Deku tries to run away, Class A draws him back by recounting their memories with him and reminding him of his own words.

As the evacuees at U.A. voice their dissent, Ochaco speaks up to try and sway them. Onlookers with ties to Izuku try to figure out if it's time for them to speak out, too.

As Izuku tries to rest and recover back at U.A. with his classmates, All Might has an encounter with Stain that leads to new information about Shigaraki and All For One.