Senior Chemist of Forensic Science Division Ko On (Raymond Wong), Senior Forensic Pathologist Man Ka-hei (Selena Lee) and Kowloon West Regional Crime Unit Senior Inspector Kwok Fai-wong (Shaun Tam) are the pillars of Crime Busting Trio leading a team of outstanding individuals. They unravel appalling schemes by using advanced forensic science. Their mastery of pathology enables them to decode secrets of the human anatomy. Their strict adherence to upholding the law never fails to uncover shocking truth about criminal acts! Unhappy childhood experience of enthusiastic reporter Tsui Yi (Roxanne Tong) surprisingly had something to do with Ko On. Seasoned forensic pathologist Queen (Alice Chan) becomes a murder suspect as she is betrayed by her lover. The Crime Busting Trio motto is “Good always triumphs over evil and embrace compassion amid animosity”. They are determined to make statements on behalf of the deceased and seek justice for survivors!