Bea es una joven con un currículum perfecto que busca su primer empleo. Tras la muerte de su madre, se ha pasado dos años dedicada en exclusiva al cuidado de su padre, pero ahora necesita salir de casa y trabajar. En su vida laboral tan sólo tiene un pequeño problema: es muy fea, hasta el punto que nadie la contrata.

Consciente de esta limitación, se presenta a una entrevista para secretaria de presidencia en la revista “Bulevar 21” sin haber enviado antes su foto. Allí tendrá un breve encuentro con Álvaro, el nuevo director de la revista, que ha llegado al puesto con fuertes opositores y con una sombra en su elección: la desaparición de Sandra, una de las accionistas.

Bea no tiene más remedio que confesarle a su padre que está buscando trabajo y que se ha presentado a una entrevista. Lo que no le cuenta es que se trata de un puesto de secretaria. A pesar de todo, Carmelo no lo ve con buenos ojos.

Mientras tanto, todos siguen buscando a Sandra. En su búsqueda, Álvaro acude a su apartamento y encuentra sangre en la bañera.

Cuando Bea ya da por perdido el empleo y piensa que se quedará eternamente cuidando de su padre, recibe una llamada de la revista para incorporarse a su nuevo puesto de secretaria. Debido a un malentendido, ella es contratada para un puesto inferior y es la explosiva Bárbara la que verdaderamente ocupa la vacante de secretaria.

Por su parte, Álvaro sigue en el punto de mira de Diego de la Vega, hermano de su novia Cayetana, que le acusa de la desaparición de su hermana Sandra.

Bea se traslada a su nuevo lugar de trabajo, un trastero contiguo al despacho de Álvaro. En la revista todo está preparado para la despedida de don Francisco y la presentación oficial de Álvaro como nuevo director general. Cayetana insta a Álvaro para que aproveche la ocasión y haga pública la contratación de su nueva secretaria y es entonces cuando descubre que Bea también ha sido contratada.

Álvaro decide que Bea se encargue de llevar su agenda personal, para sorpresa de la propia Bárbara. Por su parte, Diego sigue intentando hacerse con las cintas de seguridad que podrían inculpar a Álvaro en la desaparición de Sandra de la Vega.

Bea ayuda eficazmente a Álvaro a elaborar el discurso con el que se dirigirá a los medios como nuevo director general de “Bulevar 21”, lo que contribuye a hacerle olvidar la torpeza de la secretaria, que ha destruido inadvertidamente las cintas que podrían exculparlo de la desaparición de Sandra.

Cayetana consigue que Álvaro le pida matrimonio en el acto de presentación, pero en ese momento irrumpe Bea con el discurso que Álvaro se había dejado olvidado.

Como se muestra discreta con las cuestiones de su agenda, Álvaro recupera la confianza en Bea después del escándalo que montó en la presentación del número especial de verano.

Por su parte, Cayetana vive un momento dulce en su relación con Álvaro después de que él anunciara su compromiso de boda. Sin embargo, algo está a punto de empañar la felicidad de la pareja: Diego ha conseguido que el portero del edificio de Sandra identifique a Álvaro como el hombre que cenó con ella la noche de su desaparición.

Por otra parte, Chusa recibe un nuevo palo sentimental cuando el bombero con el que sale la deja al enterarse de que es madre.

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