In the run-down slums of a futuristic city, the boxer only known as Junk Dog is making a living throwing fights for the mob in underground arenas. That all changes when he has a chance encounter with the champion, Yuri.

Yuri has sought Junk Dog out to test his mettle in the ring, and their encounter will leave the underground fighter a changed man.

Nanbu and Joe are preparing for their first official match, but in order to do that, they'll need to find a decent set of Gear first. While searching, they run into a group of orphan boys, thieving their way through life.

JD faces off against his first opponent, hothead Shark ‘Maneater’ Samejima, with a revolutionary gimmick that will take the rest of the boxing world by storm!

Aragaki is a formidable fighter who aims to destroy Joe at the watchful eye of Nanbu, but Joe will not give up and will follow the teachings of his coach until the end

There's one month until Megalonia begins, and it looks like Shirato Yukiko's brother, Mikio, is a lock for the final entrant into the tournament. Will Joe and Team Nowhere find a way to secure their spot in the Megalo Box championship tournament?

Shirato Mikio has forced Team Nowhere to forfeit a match by threatening to expose Joe and Nanbu's seedy past. Will their dream of making it into the Megalonia tournament ever come true?

It's man vs machine, as "Gearless" Joe squares off against Shirato Mikio, who is guided by Ace, an artificial intelligence of his own design.

Crime boss Fujimaki has decided that Team Nowhere needs to throw their opening match in Megalonia in order to repay their debt to him. Can the team survive this blow to their ambitions? And even if they do, and Joe wins, will they survive the gangster's wrath?

Joe faces off against the bloody lion, Glen Burroughs. If he wants his friends to live, he'll have to throw the match. After coming this far... is there nothing else Team Nowhere can do?

Inspired by Joe's meteoric rise, and wanting to face him in a fair fight, Yuri makes a decision that will change everything for himself and Yukiko.

Joe has risen to the top and finally gets his chance of a rematch with Yuri. Yuri himself also feels joy in his chance to fight with Joe. The final battle begins!