A local FBI case involving two murdered women and a sea of powerful men turns into a manhunt for the dangerous leader of a far-reaching criminal enterprise.

The crossover starts on FBI S04E01 All That Glitters (I). It continues on FBI: International S01E01 Pilot (III).

New Fugitive Task Force member Kristin Gaines joins Jess and the team, as they head to D.C. to find a dangerous fugitive from the Jan. 6 Capitol riot

When a judge known for serving harsh sentences to juveniles is murdered, the team looks into his lengthy list of cases in the hunt for his killer. Also, Kristin faces family hurdles while resettling with her teenage daughter in New York City.

The team must determine if the kidnapping of a young Chinese-American woman is a random hate crime or if she was specifically targeted, in order to find her. Also, Jess and Sarah struggle with Tali’s continued rebellious streak.

After a deadly fire at an arcade, the team discovers the blaze was just the first step in an intricate plan to exact revenge on one of the victims. Also, Hana rejoins the team, finding new adjustments in all aspects of her life.

The team attempts to hunt down a family annihilator before he continues his murder spree. Also, Barnes’ intrusive mother puts pressure on her marriage.

The team investigates the murder of a professional basketball player’s wife, who was a famous lifestyle guru. Also, Kristin and her ex-husband grow closer, and Special Agent in Charge Isobel Castille checks in with the team on the high-profile case.

After a prized Kentucky racehorse is stolen and its groomer is taken hostage, the team quickly learns they may be the only ones who consider the young woman’s safety a priority over the horse’s. Also, Byron returns to celebrate the holidays with Jess and his family.

While holiday shopping, Barnes and Jess are caught in the middle of a mall shooting, with the exits rigged so no one can escape. Also, Gaines, Hana and Ortiz try to help from the outside, knowing their team's family members are inside and at risk.

The team hunts for a young man who is using napalm-style bombs to attack his targets. Also, with Tali away, Jess and Sarah begin to adjust to their empty nest.

The Fugitive Task Force chases a killer who plays a twisted game of cat and mouse with his victims. Also, Hana shares something personal about herself with her new roommate, Ortiz.

The team searches for a notorious Colombian drug lord after he escapes from a U.S. prison. Also, Kristin begins to open up to her ex-husband about her past.

The team searches for a businessman wanted for murder and an embezzlement scheme. Also, Jess takes advantage of his empty nest to properly court Sarah.

The team pursues an abusive man on the war path to find his ex-girlfriend, who is trying to escape him for good. Also, Jess and Sarah make plans to take their dream vacation together.

The team must track down a murderous member of the incel community targeting those he believes never give him a chance. Also, Barnes, Hana, Ortiz and Kristin deal with their grief in the wake of Jess’ death.

The team gets called to Vermont after a married couple who grow illegal marijuana massacres their employees. Also, Barnes begins to regret not taking any time off to bond with her new baby.

The team's new leader, charming but formidable Special Agent Remy Scott, takes charge as they investigate a series of homicides tied to a forbidden love between a young teen and her older boyfriend.

Remy and the team investigate the homicides of two Army veterans in a murder spree connected to their time in Afghanistan.

The team searches for a murderer recreating the chilling killings of a notorious ‘80s mobster.

When a wealthy East Hamptons couple are killed by a female con artist posing as a personal trainer, the team works to find out her true identity and track her down. Also, Ortiz is put in a tough place when Hana's brother asks a favor.

The team chases an oligarch who goes on a terror spree in New York City in a desperate attempt to escape his impossible situation.